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Florian Greten Profile Page
Florian Greten
Research Area: Molecular Medicine|*|Oncology
Research Topic: Animal Models of inflammation and cancer
Research Summary: Prof. Greten’s research interests are signal transduction in cells of the tumor microenvironment and translational oncology using suitable mouse models.

Prof. Greten (b. 1972) studied at the Universities of Hamburg and Vienna. He graduated from Hamburg University in 1998 and started working as a junior doctor at the medical clinic of Ulm University. From 2001 to 2004, he was a postdoctoral researcher at the University of California in San Diego, supported by a German Research Foundation (DFG) grant. From October 2004 to December 2010, he worked in the 2nd medical clinic of TUM’s rechts der Isar clinic. From 2005 to 2010, he completed his postdoctoral studies as director of the Emmy-Noether junior research group at TUM. Since then, he has also worked as a junior faculty member of the International Max Planck Research School for Molecular and Life Sciences. In August 2010, he was appointed associate professor of molecular gastroenterological oncology and has been working at the Institute of Molecular Immunology since January 2011.

Prof. Greten still has students in the program, but is not accepting any new students as he has taken on a position at another university.
Lab website:
Selected Publications: Bennecke et al: "Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis". Cancer Cell. 2010; 18: 135-146.

Bollrath et al: "gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis". Cancer Cell. 2009; 15(2): 91-102.

Greten FR et al: "NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ". Cell, 2007,130(5): 918-31.

Karin M, Greten FR: "NF-B: linking inflammation and immunity to cancer development and progression". Nat. Rev. Immunol. 2005; 5(10): 749-59.

Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M: "IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer". Cell. 2004; 118 (3): 285-296.